Prevention and Treatment of Molybdenum Poisoning
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- Category: Molybdenum knowledge
- Published on 11 September 2013
- Written by 陈桂兰
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Molybdenum is excreted in the milk; the concentration depends on levels in the feed. When animals are removed from the source, molybdenum is rapidly excreted. Because there is minimal tissue retention, products from exposed animals are soon safe for consumption. Signs of severe acute toxicosis are reversed by providing copper sulfate in the diet. The copper-thiomolybdate complexes reduce bioavailability, while sulfate competes with molybdenum in the gut and kidneys, reducing molybdenum absorption and enhancing its excretion. In areas where the molybdenum content of the forage is <5 mg/kg, the use of 1% copper sulfate (CuSO4?5H2O) in salt has provided satisfactory control of molybdenosis. With higher levels of molybdenum, 2% copper sulfate has been successful; up to 5% has been used in a few regions where the molybdenum levels are very high. In areas where, for various reasons, cattle do not consume mineral supplements, the required copper may be supplied as a drench given weekly, as parenterally administered repository copper preparations, or as a top-dressing to the pasture. Copper glycinate injectable has been used successfully as an adjunct to therapy.
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