Physiological and Genotoxic Effects of Molybdenum-Induced Copper Deficiency in Cattle
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- Category: Molybdenum knowledge
- Published on 19 June 2013
- Hits: 393
Molybdenosis is a disease caused by the depressing effect of molybdenum (Mo) on the physiological availability of Copper (Cu). The present study was carried out in order to analyze the ability of Mo to cause damage on the DNA integrity and changes in membrane fatty acids by oxidative damage.
Holstein male calves were fed a Mo-supplemented diet for 9 months. Variables evaluated were plasma Cu concentration, erythrocyte Cu content and SOD activity, comet assay and analysis of the fatty acid composition of erythrocyte membranes.
The statistical design was a completely randomized with one single factor and two replications. Copper plasma concentration, erythrocyte copper concentration and Cu/Zn SOD activity were analyzed using the test.
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